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UF Health University of Florida

Department of Ophthalmology Research

College of Medicine

Cristhian J Ildefonso

Cristhian J Ildefonso

Assistant Professor

Department: MD-OPHTHALMOLOGY
Business Phone: (352) 273-8786
Business Email: ildefons@ufl.edu

Publications

2019
Co-Delivery of a Short-Hairpin RNA and a shRNA-Resistant Replacement Gene with Adeno-Associated Virus: An Allele-Independent Strategy for Autosomal-Dominant Retinal Disorders
Methods in Molecular Biology
2019
Systematic Injection of Low-Dose LPS Transiently Improves the Retina Function and Structure of a Mouse Model of Geographic Atrophy
Advances in Experimental Medicine and Biology
2016
The NLRP3 Inflammasome and its Role in Age-Related Macular Degeneration
Advances in Experimental Medicine and Biology
2016
Conditional Induction of Oxidative Stress in RPE: A Mouse Model of Progressive Retinal Degeneration
Advances in Experimental Medicine and Biology

Grants

July 2017 – September 2019
Local and Systemic Inflammation in a Mouse Model of RPE-oxidative Damage
BRIGHTFOCUS FOU · Principal Investigator
August 2016 ACTIVE
Testing Gene Therapy in Models of Geographic Atrophy
NATL INST OF HLTH NEI ·

Patents

Published March 2015
Use Of Aav-Expressed M013 Protein As An Anti-Inflammatory Therapeutic
#US2016/0376325
Published February 2015
Delivery of NRF2 as Therapy for Protection Against Reactive Oxygen Species
#US2017/0088593
Published March 2014
Anti-Inflammatory AAV Vector Targeting Inflammasome Mediated Activation of Caspase-1
#US-2016-0017012

Contact Details

Phones:
Business:
(352) 273-8786
Emails:
Business:
ildefons@ufl.edu