James H Mcdowell, PhD
Scientist Emeritus
Publications
Academic Articles
2013
Formation of lipofuscin-like material in the RPE Cell by different components of rod outer segments.
Experimental eye research.
112:57-67
[DOI] 10.1016/j.exer.2013.04.006.
[PMID] 23603319.
2013
Light-dependent phosphorylation of Bardet-Biedl syndrome 5 in photoreceptor cells modulates its interaction with arrestin1.
Cellular and molecular life sciences : CMLS.
70(23):4603-16
[DOI] 10.1007/s00018-013-1403-4.
[PMID] 23817741.
2012
Aav-Mediated Gene Therapy in Mouse Models of Recessive Retinal Degeneration
Current Molecular Medicine.
12:316-330
2011
Interaction of arrestin with enolase1 in photoreceptors.
Investigative ophthalmology & visual science.
52(3):1832-40
[DOI] 10.1167/iovs.10-5724.
[PMID] 21051714.
2011
Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells.
Journal of immunology (Baltimore, Md. : 1950).
187(4):1977-85
[DOI] 10.4049/jimmunol.1101247.
[PMID] 21765017.
2008
A high-throughput screening method for small-molecule pharmacologic chaperones of misfolded rhodopsin.
Investigative ophthalmology & visual science.
49(7):3224-30
[DOI] 10.1167/iovs.07-1539.
[PMID] 18378578.
2006
Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis.
Molecular therapy : the journal of the American Society of Gene Therapy.
13(3):565-72
[PMID] 16223604.
2004
The surface of visual arrestin that binds to rhodopsin.
Molecular vision.
10:392-8
[PMID] 15215746.
2001
Activation of arrestin: requirement of phosphorylation as the negative charge on residues in synthetic peptides from the carboxyl-terminal region of rhodopsin.
Investigative ophthalmology & visual science.
42(7):1439-43
[PMID] 11381044.
1999
Identification of regions of arrestin that bind to rhodopsin.
Biochemistry.
38(9):2752-61
[PMID] 10052946.
1999
Sulfhydryl reactivity demonstrates different conformational states for arrestin, arrestin activated by a synthetic phosphopeptide, and constitutively active arrestin.
Biochemistry.
38(19):6119-25
[PMID] 10320338.
Contact Details
Phones:
- Business:
- (352) 231-0246
Emails:
- Business:
- jmcdowel@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100284
GAINESVILLE FL 32610 - Business Street:
-
J. HUGH MCDOWELL
PO BOX 100284
J. HUGH MCDOWELL
GAINESVILLE FL 326100284