Aav-Mediated Gene Therapy in Mouse Models of Recessive Retinal Degeneration
Current Molecular Medicine. 12:316-330
Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis.
Molecular therapy : the journal of the American Society of Gene Therapy. 13(3):565-72 [PMID] 16223604.
The surface of visual arrestin that binds to rhodopsin.
Molecular vision. 10:392-8 [PMID] 15215746.
Activation of arrestin: requirement of phosphorylation as the negative charge on residues in synthetic peptides from the carboxyl-terminal region of rhodopsin.
Investigative ophthalmology & visual science. 42(7):1439-43 [PMID] 11381044.
Identification of regions of arrestin that bind to rhodopsin.
Biochemistry. 38(9):2752-61 [PMID] 10052946.
Sulfhydryl reactivity demonstrates different conformational states for arrestin, arrestin activated by a synthetic phosphopeptide, and constitutively active arrestin.
Biochemistry. 38(19):6119-25 [PMID] 10320338.