Mark B Sherwood

Mark B Sherwood, MD

Professor

Department: Small Animal Clinical Sciences
Business Phone: (352) 273-8777
Business Email: sherwood@ufl.edu

About Mark B Sherwood

Dr. Sherwood, a professor of ophthalmology and Director of the Center for Vision Research, has been with the University of Florida since 1986. He received his medical degree at Manchester University in Manchester, England, and trained in ophthalmology at St. Thomas’ Hospital in London and Moorfields Hospital in London. He completed two glaucoma fellowships, the first at Moorfields Hospital and the second at Wills Eye Hospital in Philadelphia, PA. Dr. Sherwood has received the American Academy of Ophthalmology’s Honor Award and is listed in the Best Doctors in America for his work in glaucoma.

Clinical Profile

Specialties
  • Ophthalmology
Areas of Interest
  • Glaucoma

Publications

2021
A new, minimally invasive procedure for dogs with encapsulated Ahmed drainage implants and elevated intraocular pressures: A case series.
Veterinary ophthalmology. 24 Suppl 1:199-206 [DOI] 10.1111/vop.12834. [PMID] 33196139.
2021
Bilateral anterior segment dysgenesis and persistent fetal vasculature associated with terminal 10q26 deletion.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus. [DOI] 10.1016/j.jaapos.2021.05.014. [PMID] 34582953.
2021
Comparison of Outcomes of Glaucoma Drainage Implant Surgery With or Without Prior Failed Trabeculectomy.
Journal of glaucoma. 30(7):585-595 [DOI] 10.1097/IJG.0000000000001852. [PMID] 33867503.
2021
Trabeculectomy Must Survive!
Ophthalmology. Glaucoma. 4(1):1-2 [DOI] 10.1016/j.ogla.2020.08.009. [PMID] 33132096.
2019
Attaining Intraocular Pressure of ≤10 mm Hg: Comparison of Tube and Trabeculectomy Surgery in Pseudophakic Primary Glaucoma Eyes.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.). 8(6):489-500 [DOI] 10.1097/01.APO.0000605088.02788.6d. [PMID] 31789652.
2019
Modulating Ocular Scarring in Glaucoma Filtration Surgery Using the Epigenetic Adjunct Suberoylanilide Hydroxamic Acid.
Journal of current glaucoma practice. 13(1):37-41 [DOI] 10.5005/jp-journals-10078-1246. [PMID] 31496560.
2018
Comparing glaucomatous disc change using stereo disc viewing and the MatchedFlicker programme in glaucoma experts and trainees.
The British journal of ophthalmology. 102(3):358-363 [DOI] 10.1136/bjophthalmol-2017-310336. [PMID] 28814418.
2018
The impact of conjunctival flap method and drainage cannula diameter on bleb survival in the rabbit model.
PloS one. 13(5) [DOI] 10.1371/journal.pone.0196968. [PMID] 29795580.
2017
Relationship between Glaucoma Drainage Device Size and Intraocular Pressure Control: Does Size Matter?
Journal of current glaucoma practice. 11(1):1-2 [DOI] 10.5005/jp-journals-10008-1212. [PMID] 28138210.
2017
Retrospective Comparison of Intermediate-term Efficacy of 350 mm2 Glaucoma Drainage Implants and Medium-sized 230-250 mm2 Implants.
Journal of current glaucoma practice. 11(1):8-15 [DOI] 10.5005/jp-journals-10008-1214. [PMID] 28138212.
2016
Comparing Glaucomatous Disc Change Using Stereo Disc Viewing and the MatchedFlicker Software Program in Ophthalmologists-in-Training.
American journal of ophthalmology. 167:88-95 [DOI] 10.1016/j.ajo.2016.03.031. [PMID] 27038890.
2016
Mid-term Clinical Results of CO2 Laser-assisted Sclerectomy Surgery (CLASS) for Open-Angle Glaucoma Treatment.
Journal of glaucoma. 25(12):946-951 [PMID] 27782950.
View on: PubMed
2016
Porosity of Bleb Capsule declines rapidly with Fluid Challenge.
Journal of current glaucoma practice. 10(3):91-96 [PMID] 27857488.
View on: PubMed
2015
Failed glaucoma drainage implant: long-term outcomes of a second glaucoma drainage device versus cyclophotocoagulation.
The British journal of ophthalmology. 99(12):1718-24 [DOI] 10.1136/bjophthalmol-2015-306725. [PMID] 26024673.
2015
Sequential Therapy with Saratin, Bevacizumab and Ilomastat to Prolong Bleb Function following Glaucoma Filtration Surgery in a Rabbit Model.
PloS one. 10(9) [DOI] 10.1371/journal.pone.0138054. [PMID] 26394037.
2014
Probable Association of an Attack of Bilateral Acute Angle-Closure Glaucoma With Duloxetine.
The Annals of pharmacotherapy. 48(7):936-939 [PMID] 24732786.
View on: PubMed
2014
Randomized, prospective, comparative trial of EX-PRESS glaucoma filtration device versus trabeculectomy (XVT study).
American journal of ophthalmology. 157(2):433-440.e3 [DOI] 10.1016/j.ajo.2013.09.014. [PMID] 24210765.
2013
Preclinical potency and safety studies of an AAV2-mediated gene therapy vector for the treatment of MERTK associated retinitis pigmentosa.
Human gene therapy. Clinical development. 24(1):23-8 [DOI] 10.1089/humc.2013.037. [PMID] 23692380.
2013
Prevention of ocular scarring after glaucoma filtering surgery using the monoclonal antibody LT1009 (Sonepcizumab) in a rabbit model.
Journal of glaucoma. 22(2):145-51 [DOI] 10.1097/IJG.0b013e31822e8c83. [PMID] 21946553.
2012
Comparison of single versus multiple injections of the protein saratin for prolonging bleb survival in a rabbit model.
Investigative ophthalmology & visual science. 53(12):7625-30 [DOI] 10.1167/iovs.12-10120. [PMID] 23033390.
2012
Five-year outcomes of eyes with glaucoma drainage device and penetrating keratoplasty.
Journal of glaucoma. 21(9):608-14 [DOI] 10.1097/IJG.0b013e31821db3e5. [PMID] 21602705.
2012
Prevention of ocular scarring post glaucoma filtration surgery using the inflammatory cell and platelet binding modulator saratin in a rabbit model.
PloS one. 7(4) [DOI] 10.1371/journal.pone.0035627. [PMID] 22558182.
2012
Wound modulation after filtration surgery.
Survey of ophthalmology. 57(6):530-50 [DOI] 10.1016/j.survophthal.2012.01.008. [PMID] 23068975.
2011
Ab-externo AAV-mediated gene delivery to the suprachoroidal space using a 250 micron flexible microcatheter.
PloS one. 6(2) [DOI] 10.1371/journal.pone.0017140. [PMID] 21347253.
2007
Development of a microarray chip for gene expression in rabbit ocular research.
Molecular vision. 13:164-73 [PMID] 17293780.
View on: PubMed
2006
A sequential, multiple-treatment, targeted approach to reduce wound healing and failure of glaucoma filtration surgery in a rabbit model (an American Ophthalmological Society thesis).
Transactions of the American Ophthalmological Society. 104:478-92 [PMID] 17471357.
View on: PubMed
2006
Twice-daily 0.2% brimonidine-0.5% timolol fixed-combination therapy vs monotherapy with timolol or brimonidine in patients with glaucoma or ocular hypertension: a 12-month randomized trial.
Archives of ophthalmology (Chicago, Ill. : 1960). 124(9):1230-8 [PMID] 16966616.
View on: PubMed
2004
A new model of glaucoma filtering surgery in the rat.
Journal of glaucoma. 13(5):407-12 [PMID] 15354080.
View on: PubMed
2004
Expression of connective tissue growth factor after glaucoma filtration surgery in a rabbit model.
Investigative ophthalmology & visual science. 45(2):485-91 [PMID] 14744889.
View on: PubMed
2004
Functional and structural analysis of the visual system in the rhesus monkey model of optic nerve head ischemia.
Investigative ophthalmology & visual science. 45(6):1830-40 [PMID] 15161847.
View on: PubMed
2004
Is addition of a third or fourth antiglaucoma medication effective?
Journal of glaucoma. 13(2):130-6 [PMID] 15097258.
View on: PubMed
2004
Microarray analysis of the failure of filtering blebs in a rat model of glaucoma filtering surgery.
Investigative ophthalmology & visual science. 45(12):4450-62 [PMID] 15557454.
View on: PubMed
2004
Time-specific intraocular pressure curves in Rhesus macaques (Macaca mulatta) with laser-induced ocular hypertension.
Veterinary ophthalmology. 7(1):23-7 [PMID] 14738503.
View on: PubMed
2003
Corneal thickness and endothelial cell density measured by non-contact specular microscopy and pachymetry in Rhesus macaques (Macaca mulatta) with laser-induced ocular hypertension.
Experimental eye research. 76(6):671-7 [PMID] 12742349.
View on: PubMed
2003
Long-term effect of retinal ganglion cell axotomy on the histomorphometry of other cells in the porcine retina.
Journal of glaucoma. 12(4):307-15 [PMID] 12897575.
View on: PubMed
2003
Passive attenuation of cortical pattern evoked potentials with increasing body weight in young male rhesus macaques.
Documenta ophthalmologica. Advances in ophthalmology. 106(3):231-8 [PMID] 12737499.
View on: PubMed
2001
Six-month comparison of bimatoprost once-daily and twice-daily with timolol twice-daily in patients with elevated intraocular pressure.
Survey of ophthalmology. 45 Suppl 4:S361-8 [PMID] 11434939.
View on: PubMed
2000
Enhanced short-term plasmid transfection of filtration surgery tissues.
Investigative ophthalmology & visual science. 41(13):4158-62 [PMID] 11095609.
View on: PubMed
1999
A randomized trial of the effect of midazolam on intraocular pressure.
Journal of glaucoma. 8(3):204-7 [PMID] 10376262.
View on: PubMed
1999
Mid-peripheral pattern electrical retinal responses in normals, glaucoma suspects, and glaucoma patients.
The British journal of ophthalmology. 83(1):15-23 [PMID] 10209428.
View on: PubMed
1998
Change in intraocular pressure during long-term use of loteprednol etabonate.
Journal of glaucoma. 7(4):266-9 [PMID] 9713785.
View on: PubMed
1998
Diurnal intraocular pressure curves in healthy rhesus macaques (Macaca mulatta) and rhesus macaques with normotensive and hypertensive primary open-angle glaucoma.
Journal of glaucoma. 7(2):128-31 [PMID] 9559500.
View on: PubMed
1998
Glaucoma’s impact on quality of life and its relation to clinical indicators. A pilot study.
Ophthalmology. 105(3):561-6 [PMID] 9499791.
View on: PubMed
1998
Latanoprost treatment for glaucoma: effects of treating for 1 year and of switching from timolol. United States Latanoprost Study Group.
American journal of ophthalmology. 126(3):390-9 [PMID] 9744372.
View on: PubMed
1998
Signs of glaucoma in rhesus monkeys from a restricted gene pool.
Journal of glaucoma. 7(5):343-8 [PMID] 9786564.
View on: PubMed
1998
The Glaucoma Symptom Scale. A brief index of glaucoma-specific symptoms.
Archives of ophthalmology (Chicago, Ill. : 1960). 116(7):861-6 [PMID] 9682698.
View on: PubMed
1997
Influence of glaucomatous visual field loss on health-related quality of life.
Archives of ophthalmology (Chicago, Ill. : 1960). 115(6):777-84 [PMID] 9194730.
View on: PubMed
1997
Results of intraoperative 5-fluorouracil or lower dose mitomycin-C administration on initial trabeculectomy surgery.
Journal of glaucoma. 6(2):104-10 [PMID] 9098818.
View on: PubMed
1997
Treatment of bleb leaks with transforming growth factor-beta in the rabbit model.
Investigative ophthalmology & visual science. 38(8):1630-4 [PMID] 9224292.
View on: PubMed
1996
Injection of autologous blood for bleb leaks in New Zealand white rabbits.
Investigative ophthalmology & visual science. 37(11):2356-61 [PMID] 8843921.
View on: PubMed
1996
Neovascular glaucoma after carotid endarterectomy.
Ophthalmic surgery and lasers. 27(10):881-4 [PMID] 8895212.
View on: PubMed
1995
Comparison of the Baerveldt glaucoma implant with the double-plate Molteno drainage implant.
Archives of ophthalmology (Chicago, Ill. : 1960). 113(4):444-7 [PMID] 7710393.
View on: PubMed
1995
Use of scheimpflug photography to study iris configuration in patients with pigment dispersion syndrome and pigmentary glaucoma.
Journal of glaucoma. 4(6):398-405 [PMID] 19920706.
View on: PubMed
1994
Activation and suppression of fibroblast function.
Eye (London, England). 8 ( Pt 2):188-95 [PMID] 7958020.
View on: PubMed
1993
Dangers of direct injection of antimetabolites into filtration blebs.
Eye (London, England). 7 ( Pt 3):481-2 [PMID] 8224315.
View on: PubMed
1993
Drainage tube implants in the treatment of glaucoma following penetrating keratoplasty.
Ophthalmic surgery. 24(3):185-9 [PMID] 8483569.
View on: PubMed
1993
Effects of intraoperative 5-fluorouracil or mitomycin C on glaucoma filtration surgery in the rabbit.
Ophthalmology. 100(3):367-72 [PMID] 8460007.
View on: PubMed
1993
Filtration surgery as the initial therapy for open-angle glaucoma.
Journal of glaucoma. 2(1):64-7 [PMID] 19920487.
View on: PubMed
1993
Initial treatment of glaucoma: surgery or medications.
Survey of ophthalmology. 37(4):293-305 [PMID] 8441955.
View on: PubMed
1993
Intraoperative 5-fluorouracil for filtration surgery in the rabbit.
Investigative ophthalmology & visual science. 34(12):3313-9 [PMID] 8225866.
View on: PubMed
1993
Prevention of early hypotony associated with Molteno implants by a new occluding stent technique.
Ophthalmology. 100(1):85-90 [PMID] 8433833.
View on: PubMed
1993
Primary open angle glaucomas in the rhesus monkey.
The British journal of ophthalmology. 77(5):302-10 [PMID] 8318468.
View on: PubMed
1993
Prolonged localized tissue effects from 5-minute exposures to fluorouracil and mitomycin C.
Archives of ophthalmology (Chicago, Ill. : 1960). 111(2):263-7 [PMID] 8431167.
View on: PubMed
1992
A primate model for age related macular drusen.
The British journal of ophthalmology. 76(1):11-6 [PMID] 1739683.
View on: PubMed
1992
Comparison of the double-plate Molteno drainage implant with the Schocket procedure.
Archives of ophthalmology (Chicago, Ill. : 1960). 110(9):1246-50 [PMID] 1520111.
View on: PubMed
1992
Five-minute treatments with fluorouracil, floxuridine, and mitomycin have long-term effects on human Tenon’s capsule fibroblasts.
Archives of ophthalmology (Chicago, Ill. : 1960). 110(8):1150-4 [PMID] 1386726.
View on: PubMed
1992
Intraoperative and post operative treatment with 5-fluorouracil and mitomycin-c: long term effects in vivo on subconjunctival and scleral fibroblasts.
International ophthalmology. 16(4-5):381-5 [PMID] 1428576.
View on: PubMed
1992
Lens-induced endophthalmitis after Nd:YAG laser iridotomy.
American journal of ophthalmology. 113(1):97-8 [PMID] 1728154.
View on: PubMed
1992
Molteno implants in children.
Journal of glaucoma. 1(4):228-32 [PMID] 18079648.
View on: PubMed
1992
Pituitary apoplexy precipitating acute angle closure.
Archives of ophthalmology (Chicago, Ill. : 1960). 110(12):1687-8 [PMID] 1463404.
View on: PubMed
1992
Results of intraoperative 5-fluorouracil supplementation on trabeculectomy for open-angle glaucoma.
American journal of ophthalmology. 114(6):737-41 [PMID] 1463044.
View on: PubMed
1992
The effect of diclofenac sodium ophthalmic solution on intraocular pressure following cataract extraction.
Ophthalmic surgery. 23(3):170-5 [PMID] 1574284.
View on: PubMed
1990
The effect of stimulus size on the measured threshold values in automated perimetry.
Ophthalmology. 97(3):371-4 [PMID] 2336276.
View on: PubMed
1989
Long-term morphologic effects of antiglaucoma drugs on the conjunctiva and Tenon’s capsule in glaucomatous patients.
Ophthalmology. 96(3):327-35 [PMID] 2710524.
View on: PubMed
1989
Surgical treatment of progressive visual loss in traumatic optic neuropathy. Report of two cases.
Journal of neurosurgery. 70(5):799-801 [PMID] 2709121.
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1988
Pharmacokinetics of a 5-fluorouracil liposomal delivery system.
The British journal of ophthalmology. 72(9):688-91 [PMID] 3179257.
View on: PubMed
1987
Cysts of Tenon’s capsule following filtration surgery. Medical management.
Archives of ophthalmology (Chicago, Ill. : 1960). 105(11):1517-21 [PMID] 3675283.
View on: PubMed
1987
Extracapsular cataract extraction and posterior chamber intraocular lens implantation combined with trabeculectomy in patients with glaucoma.
American journal of ophthalmology. 104(5):465-70 [PMID] 3674181.
View on: PubMed
1987
Laser trabeculoplasty as supplementary treatment for primary open angle glaucoma.
The British journal of ophthalmology. 71(3):188-91 [PMID] 3828273.
View on: PubMed
1987
Surgery for refractory glaucoma. Results and complications with a modified Schocket technique.
Archives of ophthalmology (Chicago, Ill. : 1960). 105(4):562-9 [PMID] 3566614.
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1987
Use of one-piece valved tube and variable surface area explant for glaucoma drainage surgery.
Ophthalmology. 94(9):1079-84 [PMID] 3684225.
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1986
A one-piece drainage system for glaucoma surgery.
Transactions of the ophthalmological societies of the United Kingdom. 105 ( Pt 6):657-64 [PMID] 3477894.
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1986
The “Schocket” procedure: anterior chamber tube shunt to an encircling band.
Journal of ophthalmic nursing & technology. 5(5):187-92 [PMID] 3639164.
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1985
Argon laser trabeculoplasty in exfoliation glaucoma. A retrospective analysis.
Developments in ophthalmology. 11:116-23 [PMID] 4018352.
View on: PubMed
1985
Argon laser trabeculoplasty in exfoliation syndrome.
The British journal of ophthalmology. 69(12):886-90 [PMID] 4084479.
View on: PubMed

Grants

Jun 2017 – May 2019
OR-DRPD-ROF2017: Novel Glaucoma Drainage Devices
Role: Co-Investigator
Funding: UF DSR OPPORTUNITY FUND
Oct 2015 – Jun 2019
Glaucoma Therapy by Contact Lenses-Human Trials
Role: Principal Investigator
Funding: UF DSR OPPORTUNITY FUND
Feb 2015 – Aug 2019
192024-092 The Efficacy and Safety of Bimatoprost SR in Patients with Open-angle Glaucoma or Ocular Hypertension
Role: Principal Investigator
Funding: ALLERGAN plc
Aug 2006 ACTIVE
UFF Daniels Professorship
Role: Principal Investigator
Funding: UF FOU

Education

Other Program – Ophthalmology
1980 · St. Thomas Hospital
Other Program – Neurological Surgery
1979 · Manchester Royal Eye Hospital
Other Program- Ophthalmology
1978 · Manchester Royal Eye Hospital
Internship – Surgery
1977 · Manchester Royal Infirmary
Bachelor of Medicine, Bachelor of Surgery
1976 · University of Manchester
Bachelor's of Science
1973 · St. Andrew's University

Teaching Profile

Courses Taught
2018
MDT7550 Elect Top/Opthalmol
2009
MEL7933 Elect Top/Opthalmol

Contact Details

Phones:
Business:
(352) 273-8777
Emails:
Business:
sherwood@ufl.edu