The strength of our research team here in the Department of Ophthalmology is highlighted, in part, by their funding.
John Ash, Ph.D.
- NIH/NEI, R01 EY016459-05 (Ash)
Cytokine Regulation of Photoreceptor Gene Expression
9/01/2010-8/31/2013 - Foundation Fighting Blindness (Ash)
“Using AAV-STAT3 and AAV-PIM1 vectors to induce broad-spectrum protection of photoreceptors and RPE”
6/1/2013-5/31/2016
Sanford L. Boye, M.S.
- “Retinoschisin Mouse Model Re-derivation and Efficacy Testing of AAV-RS1” (SL Boye)
Funding Agency: AGTC
Dates: 6/1/2014-5/31/2015 - “Evaluation of rAAV2tYF-CB-hRS1 Tox/BD Drug product for Transduction Efficiency and Rescue of ERG Responses in RS1 Knock-out Mice” (SL Boye and Hauswirth)
Funding Agency: AGTC
Dates: 3/4/2014-3/6/2015 - “Toxicology, Biodistribution and Efficacy Study of rAAV2tYF-CB-hRS1” (subproject- SL Boye)
Funding Agency: Applied Genetics Technologies Corporation (AGTC)
Dates: 12/10/13-12/09/14 - “Gene Therapy for LCA1” (SE Boye)
Funding Agency: Genzyme-Sanofi
Dates: 3/1/2014-2/28/2016 - “Vision Research Core” (P30EY021721)
Funding Agency: NIH/National Eye Institute
Role: Senior personnel, modules supervisor, (PI, Hauswirth)
Dates: 8/1/2011-7/31/2016
Shannon E. Boye, Ph.D.
- RO1EY024280 (SE Boye)
“Developing Efficient AAV Vectors for Photoreceptor Targeting via the Vitreous”
6/01/14-5/31/19 - Genzyme/Sanofi (SE Boye)
“Gene Therapy for LCA1”
4/01/14-3/31/17 - Foundation Fighting Blindness (SE Boye)
Individual Investigator Research Award
Targeting foveal cones using novel delivery methods and novel AAV serotypes
6/01/12-6/01/15 - Foundation Fighting Blindness (SE Boye)
Individual Investigator Award
“Dual AAV vector-mediated therapy for Myosin7A Usher syndrome (USH1B)”
8/01/14-7/31/16 - Foundation Fighting Blindness (Hauswirth and SE Boye)
Wynn Gund TRAP (Translational Research Acceleration Program) Award
Gene Therapy for LCA1
10/1/10-9/30/15 - AGTC Inc. Sponsored Research Agreement (SE Boye)
10/1/14-9/30/16 - AGTC Sponsored Research Agreement (Zolotukhin and SE Boye)
10/1/14-9/30/17 - Overstreet Endowment (Tuli)
University of Florida Foundation
Research in Age-Related Macular Degeneration
6/1/2014-present
William W. Hauswirth, Ph.D.
- Grant Identifier: R24 EY022023 (Hauswirth)
6/01/13-5/31/18
Sponsor: NEI
Title of Grant: rAAV-CNGB3 Gene Therapy for Achromatopsia: Translational Research Studies - Grant Identifier: P30-EY021721 (Hauswirth)
8/01/11-7/31/16
Sponsor: NEI
Title of Grant: Vision Research Center - Grant Identifier: NA (Hauswirth)
1/01/13-12/31/16
Sponsor: Macular Vision Research Foundation
Title of Grant: Gene Therapy for Blue Cone Monochromacy (BCM) - Grant Identifier: NA (Hauswirth)
7/1/13-6/30/16
Sponsor: Elden Family Foundation
Title of Grant: Gene Therapy for Ush3A - Grant Identifier: 2011445 (Banin)
10/01/12-9/30/16
Sponsor: US Israel Binational Science Foundation
Title of Grant: Gene Therapy Using Novel Viral Vectors in the CNGA3 Sheep Model of Achromatopsia - Grant Identifier: TA-GT-0911-0559-AGTC-WG (Washer)
10/01/12-9/30/16
Sponsor: Foundation Fighting Blindness
Title of Grant: AAV-based Gene Therapy for X-linked Retinoschisis - Grant Identifier: R24 EY022012 (Beltran)
3/01/12-2/28/16
Sponsor: NEI
Title of Grant: Translational Gene Therapy for Rhodopsin Autosomal Dominant Retinitis Pigmentosa - Grant Identifier: R01 EY017549 (Aguirre)
9/30/06-7/31/15
Sponsor: NEI
Title of Grant: Translational Research for Retinal Degeneration Therapies - Grant Identifier: C-GT-071-0536-UFL04 (Weleber)
7/01/11-6/30/16
Sponsor: Foundation Fighting Blindness
Title of Grant: OHSU Research Center for the Study of Retinal Degenerations - Grant Identifier: U10-EY017280 (Jacobson)
9/30/06-7/31/15
Sponsor: NEI
Title of Grant: Clinical Trials of Gene Therapy for Leber Congenital Amaurosis Type 2 - Grant Identifier: C-GT-0812-0590-UFL03 (Jacobson)
8/1/12-7/31/17
Sponsor: Foundation Fighting Blindness
Title of Grant: FFB Center at the Scheie Eye Center - Grant Identifier: FFB TA-GT-0611-0526-UF (Lewin)
6/30/14-6/29/17
Sponsor: Foundation Fighting Blindness
Title of Grant: RNA Replacement Therapy for ADRP - Grant Identifier: R01 EY012978 (Nirenberg)
2/1/13-1/31/17
Sponsor: NEI
Title of Grant: Population Coding in the Retina
Qiuhong Li, Ph.D.
- NIH RO1 (Li)
Renin Angiotensin System in Pathogenesis of Diabetic Retinopathy
1/1/2012-12/31/2015 - NIH RO1 (Grant/Raizada)
Vascular Reparative Mechanism by ACE2/Ang-(1-7) in Diabetes
7/1/2011 – 6/30/2016
Daniel M. Lipinski, D.Phil.
- Juvenile Diabetes Research Foundation (JDRF) Innovative Award (1-PNF-2014-120-A-N)
Validation of a novel AAV vector for targeted gene therapy to prevent vascular complications of diabetic retinopathy (PI: Lipinski)
5/01/2014-10/31/2015
Jijing Pang, MD, Ph.D.
- 2014 UF Faculty Enhancement Opportunity Award
- Macula Vision Research Foundation (Hauswirth and Pang)
“Vitreal delivery of novel AAV vectors for blue cone monochomacy (BCM)”
01/01/14 – 12/31/16 - R21EY023543 (Pang)
“Vitreal delivery of novel AAV vectors for CNGA3 achromatopsia cone gene therapy”
08/01/2013 – 07/31/2015 - UF and WMU agreement (Pang) to design, produce and deliver the AAV vectors to WMC
07/01/2013 – 12/31/2017 - International collaboration project by The Ministry of Science and Technology of China 2010DFB33430 (China PI: Fangtian Dong, US PI: Jijing Pang)
“Genetic diagnosis and gene therapy of inherited retinal degeneration in China”
01/01/2011 to 12/31/15
Clay Smith, Ph.D.
- NIH National Eye Institute/ R01 EY014864-06 Smith (PI)
Arrestin Migration in Photoreceptors: Mechanism/Function”
08/01/11 – 6/30/15 - NIH National Eye Institute (Smith)
“Training in Vision Sciences”
01/01/10-12/31/14 - Overstreet Foundation (Tuli)
University of Florida Foundation Research in Age-Related Macular Degeneration
10/01/11-present - Shaler-Richardson Professorship (Smith)
College of Medicine, Univ. of Florida
4/1/09-present
Sonal Tuli, M.D.
- NIH RO1 – EY 05587-25 (Co-I)
Regulation of Stromal Wound by Growth Factors - CTSI Training Award (mentor)
8/2014-8/2015